牛年牛Buy，Cytoskeleton小G蛋白产品线开学大促啦

发布者：艾美捷科技发布时间：2021-02-25

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为答谢和回馈广大科研工作者们长期以来对武汉艾美捷科技有限公司的大力支持，艾美捷科技联合细胞骨架领域顶级供应商 Cytoskeleton 联合推出：小 G 蛋白产品线超值大促，一年仅此一次，千万不要错过啊！本次促销活动产品涵盖 GEFs, 小 G 蛋白和 G-LISA 活化试剂盒等。

小 G 蛋白(Small G Protein)因分子量只有 20—30KD 而得名，同时具有 GTP 酶活性，在细胞信号通路中发挥分子开关的功能，参与调控很多生物学过程，包括分泌活动和细胞骨架的装配等。目前发现的小 G 蛋白包括 Rho, Rac, Arf1 & 6, Ras, Ral 等。小 G 蛋白的共同特点是，当结合了 GTP 时即成为活化形式，这时可作用于下游分子使之活化，而当 GTP 水解成为 GDP 时（自身为 GTP 酶）则恢复到非活化状态。

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Pull-down 和 G-LISA 实验都被广泛地用于研究小 G 蛋白的活性。Pull-down 实验又叫蛋白质体外结合实验，可用于测定活性的 GTPase 亚型，可作为对 G-LISA 实验的补充。G-LISA 实验是一种改进的 ELISA，可测定 3-D 细胞系、原代细胞裂解液及组织裂解液中有活性的 GTPase，使 GTPase 定量的准确性增加。

活动详情：

时间：2021年3月1日-2021年4月15日

对象：仅限中国区终端客户

品目：GEFs, 小 G 蛋白和 G-LISA 活化试剂盒等产品（详情见下方活动品目列表）

内容： 直享 6.5 折超低优惠！

活动品目列表：


货号	产品名称	规格	原价	促销价
ACD03	Anti-Cdc42 Mouse Monoclonal Antibody	2 x 200 µl	5454	3545
ACD03-S	Anti-Cdc42 Mouse Monoclonal Antibody (sample size)	1 x 50 µl	1533	997
ARC03	Anti-Rac1 specific mouse MAb	2 x 100 µl	5454	3545
ARC03-S	Anti-Rac1 specific mouse MAb(sample size)	1 x 25 µl	1533	997
BK008	Ras Activation Assay Biochem Kit	KIT 50 assays	11050	7182
BK008-S	Ras Activation Assay Biochem Kit	KIT 20 assays	5612	3648
BK030	Combo RhoA/Rac1/Cdc42 Activation Assay Kit	KIT 3 x 10 assays	14622	9505
BK032-S	Arf1 Pulldown Activation Assay Kit	KIT 20 assays	6718	4367
BK033-S	Arf6 Pulldown Activation Assay Kit	KIT 20 assays	6718	4367
BK034	Cdc42 Pulldown Activation Assay Kit	KIT 50 assays	11050	7182
BK034-S	Cdc42 Pulldown Activation Assay Kit	KIT 20 assays	5612	3648
BK035	Rac1 Pulldown Activation Assay Kit	KIT 50 assays	11050	7182
BK035-S	Rac1 Pulldown Activation Assay Kit	KIT 20 assays	5612	3648
BK036	RhoA Pulldown Activation Assay Kit	KIT 80 assays	11050	7182
BK036-S	RhoA Pulldown Activation Assay Kit	KIT 20 assays	5612	3648
BK040	RalA Activation Assay Biochem Kit	KIT 50 assays	11050	7182
BK100	GEF Exchange Assay	KIT 60-300 assays	10196	6628
BK105	GAP Assay Kit	KIT 80-160 assays	10196	6628
BK121	RhoA G-LISA Activation Assay (luminescence)	KIT 96 assays	13753	8939
BK124	RhoA G-LISA Activation Assay (absorbance)	KIT 96 assays	13753	8939
BK124-S	RhoA G-LISA Activation Assay (absorbance)	KIT 24 assays	8299	5394
BK124-XL	RhoA G-LISA Activation Assay (absorbance)	Large Quantities	询价	询价
BK125	Rac1,2,3 G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK126	Rac1 G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK127	Cdc42 G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK127-S	Cdc42 G-LISA Activation Assay Kit	KIT 24 assays	8299	5394
BK128	Rac1 G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK128-S	Rac1 G-LISA Activation Assay Kit	KIT 24 assays	8299	5394
BK129	RalA G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK131	Ras G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK131-XL	Ras G-LISA Activation Assay Kit	大规格	询价	询价
BK132	Arf1 G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK133	Arf6 G-LISA Activation Assay Kit	KIT 96 assays	13753	8939
BK135	G-LISA Bundle (BK135 = BK124-S + BK127-S + BK128-S)	3 KITS (24 assays/kit)	22922	14899
BK150	RhoA ELISA Kit	KIT 96 assays	7509	4881
C17G01-A	Cdc42-GST protein: dominant negative	1 x 25 µg	4110	2672
C6101-A	Cdc42-His Protein: constituitively active	1 x 10 µg	4110	2672
CD01-A	Cdc42-His Protein: Wild type	1 x 100 µg	4110	2672
CD01-C	Cdc42-His Protein: Wild type	3 x 100 µg	10038	6525
CD01-XL	Cdc42-His Protein: Wild type	1 x 1 mg	21341	13872
CDG01-C	Cdc42-GST Protein: Wild type	8 x 25 µg	7667	4983
CN01-A	Rho Activator	5 x 10 units	3146	2045
CN01-B	Rho Activator	20 x 10 units	11461	7450
CN02-A	Rac and Cdc42 Activator	5 x 10 units	3146	2045
CN02-B	Rac and Cdc42 Activator	20 x 10 units	11461	7450
CN03-A	Rho activator II	3 x 20 µg	3146	2045
CN03-B	Rho activator II	9 x 20 µg	8852	5754
CN03-XL	Rho activator II	Large Quantities	询价	询价
CN04-A	Rho/Rac/Cdc42 Activator I	3 x 20 µg	3146	2045
CN04-B	Rho/Rac/Cdc42 Activator I	9 x 20 µg	8852	5754
CS-GE03	Ras-GRF GEF protein (human recomb. CDC25 domain, MBP tagged)	1 x 100 µg	5454	3545
CS-GE04	Tiam1 GEF protein (human recomb. DHPH domain, MBP tagged)	1 x 100 µg	5454	3545
CS-GE05	Vav1 GEF protein (human recomb. DHPHC1 domain Y174D mutant, 6xHis tagged)	1 x 100 µg	5454	3545
CS-GE06	Vav2 GEF protein (human recomb. DH domain, 6xHis tagged)	1 x 100 µg	5454	3545
CS-GE07	ARNO Protein: GEF (Sec7) domain (aa31- 267, human recomb., 6xHis tagged)	1 x 100 µg	5454	3545
CS-GE08	SOS2 exchange domain (563-1051) protein (Human recombinant)	1 x 100 µg	5454	3545
CS-GE09	RAPGEF5 Protein: Ras association and exchange domain (57– 580) wild type. (Human recombinant, GST tagged)	1 x 100 µg	5454	3545
CS-RS02	N-Ras Protein; wild-type (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS03	K-Ras4B Protein: wild-type (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS04	K-Ras4B Mutant Protein: G12V (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS05	R-Ras Protein: wild-type (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS06	K-Ras4B Mutant Protein: G13D (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS07	K-Ras4B Mutant Protein: G13S (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS08	K-Ras4B Mutant Protein: K128A (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS09	K-Ras4B Mutant Protein: Q61P (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS10	K-Ras4B Mutant Protein: R135A (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS11	K-Ras4B Mutant Protein: G12D+I36N (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS12	K-Ras4B Mutant Protein: G12D+D38A (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CS-RS13	K-Ras4B Mutant Protein: G12D (human recombinant with 6xHis-tag)	1 x 100 µg	6086	3956
CT03-A	C3 transferase protein	1 x 25 µg	3146	2045
CT03-C	C3 transferase protein	4 x 25 µg	10987	7141
CT04-A	Cell Permeable Rho Inhibitor (C3 Trans based))	1 x 20 µg	3146	2045
CT04-B	Cell Permeable Rho Inhibitor (C3 Trans based))	5 x 20 µg	9406	6114
CT04-C	Cell Permeable Rho Inhibitor (C3 Trans based))	20 x 20 µg	24898	16183
CT04-XL	Cell Permeable Rho Inhibitor (C3 Trans based))	Large Quantities	询价	询价
GAP01-A	Rho GAP Protein GST	1 x 50 µg	4347	2826
GAP01-B	Rho GAP Protein GST	4 x 50 µg	10670	6936
GAS01-A	Rho GAP Protein: catalytic domain GST	1 x 50 µg	4347	2826
GAS01-B	Rho GAP Protein: catalytic domain GST	4 x 50 µg	10670	6936
GDI01-A	GDP dissociation inhibitor protein GST fusion	1 x 25 µg	4347	2826
GE01-A	Dbs protein GEF domain - HIS fusion	2 x 50 µg	4347	2826
GE02	SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)	1 x 100 µg	5138	3339
GE02-XL	SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)	1 x 1 mg	26083	16954
GGA07-A	GGA3-PBD Arf Affinity Beads	1 x 500 µg	6718	4367
PAK01-A	PAK Rac1/Cdc42 binding domain protein	1 x 250 µg	5928	3853
PAK01-B	PAK Rac1/Cdc42 binding domain protein	4 x 250 µg	15729	10224
PAK02-A	PAK Beads, Rac1/Cdc42 binding domain protein on beads	1 x 500 µg	6876	4470
PAK02-B	PAK Beads, Rac1/Cdc42 binding domain protein on beads	4 x 500 µg	21025	13666
R17G01-A	Rac1 GST Protein: dominant negative	1 x 25 µg	4110	2672
R6101-A	Rac1 His Protein: constitutively active	1 x 10 µg	4110	2672
R6301-A	RhoA His Protein: constitutively active	1 x 10 µg	4110	2672
RC01-A	Rac1 His Protein: wild type	1 x 100 µg	4505	2928
RC01-C	Rac1 His Protein: wild type	3 x 100 µg	10670	6936
RC01-XL	Rac1 His Protein: wild type	1 x 1 mg	21341	13872
RC02-A	Rac2 His Protein: wild type	1 x 100 µg	4505	2928
RCG01-C	Rac1 GST Protein: wild type	8 x 25 µg	7667	4983
RF02-A	Raf protein ras binding domain on GST beads	1 x 2 mg	7351	4778
RF02-B	Raf protein ras binding domain on GST beads	4 x 2 mg	21341	13872
RH01-A	RhoA His Protein: wild type	1 x 100 µg	4505	2928
RH01-C	RhoA His Protein: wild type	3 x 100 µg	10670	6936
RH01-XL	RhoA His Protein: wild type	1 x 1 mg	21341	13872
RH03-A	RhoC His Protein: wild type	1 x 100 µg	4505	2928
RHG01-C	RhoA GST Protein: wild type	8 x 25 µg	7667	4983
RR02-A	Rap1b protein (Human wild type, His)	1 x 100 µg	4505	2928
RS01-A	H-Ras Protein; wild type 6xHis Tag	1 x 100 µg	4505	2928
RS01-C	H-Ras Protein; wild type 6xHis Tag	3 x 100 µg	10670	6936
RT01-A	Rhotekin RBD protein GST fusion	1 x 500 µg	6718	4367
RT02-A	Rhotekin RBD protein on GST beads	2 x 2 mg	8932	5805
RT02-B	Rhotekin RBD protein on GST beads	6 x 2 mg	21341	13872
VCG03-A	VCA domain of WASP (GST fusion)	1 x 500 µg	7509	4881

* 本活动最终解释权归艾美捷科技所有

Cytoskeleton公司成立于1993年，专注于生物化学和细胞过程研究中的纯化蛋白和便捷试剂盒开发与生产。公司提供药物筛选、信号转导、蛋白质转录后修饰（PTM）、细胞骨架研究相关的系列试剂盒和产品，尤其以细胞骨架相关研究见长，既能满足于样品较少的科学研究，也可以用于小规模筛选研究和高通量大规模筛选研究。

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