- 中文名称
Epstein-Barr Nuclear Antigen, Human, IgG, BioAssay ELISA Kit (EBNA)
- 英文名字
- Epstein-Barr Nuclear Antigen, Human, IgG, BioAssay ELISA Kit (EBNA)
- 供应商
- USBiological
- 产品货号
- T8171-92F
- 产品报价
- ￥1/1Kit
- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- 产品描述
- The United States Biological Epstein-Barr Nuclear Antigen, Human, IgG, BioAssay ELISA Kit is intended for the detection of IgG antibody to Epstein Barr Virus Nuclear Antigen-1 in human sera and plasma.Detection of the Epstein-Barr virus was first described in 1964 by Epstein, Achong, and Barr using electron microscopic studies of cultured lymphoblasts derived from patients with Burkitt's lymphoma. EBV is classified as a member of the herpes-virus family based upon it's characteristic morphology. EBV infection may demonstrate a wide spectrum of clinical symptoms. The majority of primary EBV infections are transmitted via saliva, occur during childhood, and are subclinical. In the U.S., 50% of the population demonstrate EBV antibodies before the age of 5 years; 80% by adulthood. Transfusion- associated EBV infections have also been reported3. In young adults, EBV infection may be clinically manifested as Infectious Mononucleosis (IM) with typical symptoms of sore throat, fever, and lymphadenopathy. College students and military personnel are often cited as a high morbidity incidence population for IM. Infection of the target cells leads to two forms of viral cycles; 1) latent, nonproductive and 2) productive, replicative infections. In both cycles, one of the earliest antigens expressed is lymphocyte-detected membrane antigen, a cell-surface antigen recognized by T-cells. It has been well established that most individuals exposed to EBV develop a heterophile antibody response. Expression of EBNA-1 either follows or parallels membrane antigen at 12 to 24 hours post infection. EBNA-1 is found as nonstructural, intranuclear antigen(s), present in all EBV-transformed cell lines as in tumors from Burkitt's and nasopharyngeal carcinoma patients. In the fully productive, replicative cycle, the synthesis of antigen follows EBNA-1. The viral capsid antigen complex (VCA) appears late in the replicative cycle. It has recently become apparent that EBNA-1 is probably not a single antigenic moiety, but a multicomponent antigen complex, on the basis of reactivities of serum from different classes of patients. The major component EBNA-1 has been purified and sequenced in its entirety. Antibody levels of EBNA-1 IgG, are diagnostic in determining acute and convalescent stages in IM IgG antibodies to EBNA-1 are rarely present in acute IM and rise during convalescence. They will rise to a plateau level in three months to a year and will normally persist for life. Kit Components:1. Microtiter Plate: 1x96 wells2. Sample diluent: 1X22ml 3. Wash Buffer,10X: 1X100ml 4. Tetramethylbenzidine (TMB): 1x15ml5. Enzyme conjugate: 1X12 ml6. Cut-off Calibrator: 1X150ul 7. Negative control: 1X150ul 8. Positive control: 1X150ul9. Stop solution:1X12 ml (2 N Hcl) Storage and Stability:Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- 产品特点
- 针对Epstein-Barr Nuclear Antigen, Human, IgG, BioAssay ELISA Kit (EBNA)该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Epstein-Barr Nuclear Antigen, Human, IgG, BioAssay ELISA Kit (EBNA)产品后将其置于4°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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