Tissue inhibitors of metalloproteinases, or TIMPs are members of the family of tissue inhibitors of matrix metalloproteinases (MMPs). They exhibit multiple functions, including the inhibitory effect on MMPs, but they also they irreversibly inactivate MMPs by direct binding to their catalytic zinc cofactor and resultant inhibition of proteinase function. In addition they interact with various membrane receptors on the cell surface. TIMP1 in particular interacts with CD63. TIMPs are involved in a wide variety of biological functions, such as tumor angiogenesis and progression, wound healing, and vascular remodeling.
应用类型
WB | ELISA
免疫原
人 TIMP1内段合成肽.
来源宿主
兔
反应性
人 | 小鼠 | 大鼠
保存建议
厂家推荐蓝冰运输。收到产品后建议保存于-20ºC。
其他
StressMarq Biosciences Inc. 在2007年成立于加拿大维多利亚，是一家生物科技公司，专门从事试剂与试剂盒研究，服务范围遍16999多个国家。 StressMarq公司的核心技术领域为细胞应激（尤其是热休克蛋白（HSP）领域，领先全球），离子通道，载体研究，同时在神经科学领域推出特有的具有生物活性的Tau蛋白与A-突触核蛋白。产品领域涉及到：细胞凋亡、细胞信号、通路和转运、细胞器标志物、热休克、神经生物学、神经科学、氧化应激、磷酸化运输等。除了提供用于进一步研究的相关工具外，Strꮺ䈞ꡊ䈟厨䈠썪䈠䲺㓚坊䉥뀚䇭జ㑟뙪䱱ጞ䉈䉝롌⚙◢⌭䄠䇮軈㟀se
