RAP1A is part of the family of RAS-related proteins which possess 50% amino acid identity with the classical RAS proteins and have various structural characteristics in common. RAP proteins differ from RAS proteins in their 61st amino acid， glutamine in RAS is replaced by threonine in RAP proteins. RAP1A induces morphological reversion of a cell line transformed by a Ras oncogene and counteracts the mitogenic function of Ras， since it can interact with Ras GAPs and RAF in a competitive manner.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. RAP1A Human solution containing 20mM Tris HCL pH-7.5， 5mM DTT， 0.2M NaCl & 40% glycerol.
保存建议
RAP1A Human although stable at 4℃ for 1 week， should be stored desiccated below -18℃. Please prevent freeze thaw cycles.
