SGTA is a ubiquitously expressed protein that contains three TPR protein-protein interaction duplicates. SGTA takes part as a component of the androgen receptor （AR）-chaperone-cochaperone complex， functions as a cochaperone and participates in androgen signaling. SGTA acts as a cochaperone that binds directly to HSC70 and HSP70 and mediatess their ATPase activity. While being involved in apoptosis and androgen signaling， SGTA is a possible molecule for polycystic ovary syndrome， a disorder characterized by androgen excess， obesity and menstrual disturbances.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. SGTA Human solution containing 20mM Trsi HCL pH-8， 1mM DTT and 10% glycerol.
保存建议
SGTA human although stable at 4℃ for 1 week， should be stored desiccated below -18℃. Please prevent freeze thaw cycles.
