MNDA plays a role as a transcriptional activator/repressor in the myeloid lineage and in the granulocyte/monocyte cell-specific response to interferon. MNDA Stimulates the DNA binding of the transcriptional repressor protein YY1. MNDA is identified only in nuclei of cells of the granulocyte-monocyte lineage. A 200-a.a region of human MNDA is remarkably related to a region in the proteins encoded by a family of interferon-inducible mouse genes， MNDA participates in blood cell-specific responses to interferons.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The MNDA solution contains 20mM Tris-HCl buffer （pH 8.0）， 1mM DTT and 10% glycerol.
保存建议
MNDA although stable 4C for 4 weeks， should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
