GANP has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center B regions/cells. GANP is related with MCM3, a protein essential for DNA replication. Increased expression of GANP is related with malignant transformation of melanocytes. GANP functions in the regulation of DNA repair during replication and survival of B cells.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered clear solution. GANP is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store, frozen at -20℃ for longer periods of time.
Please avoid freeze thaw cycles.