ATOX1 is a metal transport protein that is part of the ATX1 family. ATOX1 is a copper chaperone that takes part in cellular antioxidant defense and can bind and deliver cytosolic copper to the copper ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. ATOX1 plays a role as an antioxidant against superoxide and hydrogen peroxide， and consequently， takes an important part in cancer carcinogenesis. Because of ATOX1 cytogenetic location， the gene can be a good a candidate gene for 5q-syndrome.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. ATOX1 solution containing 20mM Tris pH-8， 1mM DTT and 10% glycerol.
保存建议
ATOX1 Human Recombinant although stable at 4℃ for 1 week， should be stored below -18℃.
Please prevent freeze thaw cycles.
