PDCD1LG2 （B7-DC， CD273）， is part of the B7 family of proteins. PDCD1LG2 plays an important regulatory role during the immune response of the host to the pathogen.
PDCD1LG2 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia. HRV-16 infection or exposure to dsRNA induces epithelial PDCD1LG2. PDCD1LG2 functions as an inhibitor to T cell activation. PDCD1LG2 negatively regulates human T cell activation and therefore acts an a candidate protein for immunotherapeutic approaches aimed to attenuate pathological immune responses.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered clear solution. PDCD1LG2 is supplied in 50mM Tris-Acetate， pH-7.5， 1mM EDTA and 20% Glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time.
Please avoid freeze thaw cycles.
