BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2， such as in the case of translocation of BCL2 to Ig heavy chain locus， is thought to be the cause of follicular lymphoma. Two transcript variants， produced by alternate splicing， differ in their C-terminal ends.
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大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. The BCL2 protein solution contains 20mM Tris-HCl， pH-8， 2mM DTT and 20% glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles.
