TCEB2 is a subunit of the SIIII complex which is a heterotrimer consisting of a transcriptionally active subunit （A） and two regulatory subunits （B and C）. TCEB2 initiates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C， and thereby inhibits transcription elongation.
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大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The TCEB2 protein solution contains 20mM Tris-HCl pH-8， 1mM DTT， 0.1mM PMSF， and 20% glycerol.
保存建议
TCEB2 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
