C1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells.
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来源宿主
大肠杆菌中重组表达
溶解建议
Human C1QTNF3 was lyophilized from PBS, pH 7.5. Add deionized H2O to a working volume of 0.5mg/ml and let the lyophilized pellet of C1QTNF3 dissolve completely.
保存建议
Store lyophilized C1QTNF3 at -20℃. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4℃ for a limited period of time; it does not show any change after two weeks at 4℃. The lyophilized C1QTNF3 remains stable until the expiry date when stored at -20℃.