Synaptic vesicle membrane docking and fusion is mediated by SNAREs （soluble N-ethylmaleimide-sensitive factor attachment protein receptors） located on the vesicle membrane （v-SNAREs） and the target membrane （t-SNAREs）. The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices， one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane， the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore， SNAP25 product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. The synaptosomal-associated protein （SNAP-25） is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus， SNAP-25 is directly involved in the release of neurotransmitters.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The protein solution contains 20mM Tris-HCl pH7.5， 2mM EDTA， 50mM NaCl and 1mM DTT.
保存建议
SNAP25 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
