HIF1A has a role as a master transcriptional monitor of the adaptive response to hypoxia. Under hypoxic conditions HIF1A activates the transcription of over 40 genes， including， erythropoietin， glucose transporters， glycolytic enzymes，
vascular endothelial growth factor， and genes whose protein products increase oxygen release or facilitate metabolic adaptation to hypoxia. HIF1A functions as an essential role in embryonic vascularization， tumor angiogenesis and pathophysiology of ischemic disease.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. HIF1A Human solution containing 20mM Tris pH-8， 1mM DTT， 0.2M NaCl & 10% glycerol.
保存建议
HIF1A Human although stable at 4℃ for 1 week， should be stored desiccated
below -18℃.
Please prevent freeze thaw cycles.
