P504s / AMACR a-methyl-CoA Racemase is an essential enzyme in the b-oxidation of branched-chain fatty acids， it is responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their （S）-stereoisomers， which are the only stereoisomers that can be degraded via peroxisomal beta-oxidation. High expression of P504s protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-ebmbedded tissue. The expression of P504s is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia （PIN） and atypical adenomatous hyperplasia.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered clear solution. P504s at 0.1mg/ml in 50mM Tris-Acetate， pH7.5， 1mM EDTA， 20% Glycerol.
保存建议
Store vial at -20℃ to -80℃. When stored at the recommended temperature， this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
