S100A7 is a member of the S-100 family of calcium binding proteins and is produced through a non-classical secretory pathway to the cytoplasm. S100A7 takes part in the regulation of several cellular courses， such as cell cycle， cell progression and cellular differentiation. S100A7 holds two EF-hand domains and is extremely upregulated in psoriatic epidermis， in addition to bladder squamous cell carcinoma and breast cancer tissue， signifying a probable part in carcinogenesis.
