The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.
应用类型
WB,IHC,ICC
免疫原
Purified recombinant fragment of human ACTR3 (AA: 287-418) expressed in E. Coli.
