The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
应用类型
FCM
免疫原
Purified recombinant fragment of human CD154 (AA: extra 47-261) expressed in E. Coli.
