This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
应用类型
ICC,FCM
免疫原
Purified recombinant fragment of human ADAR (AA: 1085-1223) expressed in E. Coli.
