FAK is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene， but the full-length natures of only two of them have been determined.
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来源宿主
Sf9昆虫细胞中重组表达
溶解建议
提供的人粘着斑激酶（FAK1）产品为溶液形式；其中人粘着斑激酶（FAK1）产品溶解于50mM Tris pH 7.5，150mM NaCl，0.5mM EDTA，0.02% Triton X-100，2mM DTT，50%甘油溶液中.
