PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
应用类型
WB
免疫原
A synthetic phosphopeptide corresponding to residues surrounding Thr451 of human PKR
