Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.nIsoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
应用类型
WB,IP
免疫原
A synthetic peptide of human Growth hormone receptor