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细胞分析试剂盒
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中文名称

EZCell™细胞内锌染色试剂盒(基于细胞)

英文名字
EZCell™ Intracellular Zinc Staining Kit (Cell-Based)
供应商
Biovision
产品货号
K525-50
产品报价
¥询价/50assays
产品说明书
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产品新闻
背景资料
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产品描述
Zinc (Zn, Atomic Number: 30) is an essential mineral of great biological significance. It is a metal with characteristics similar to Magnesium due to its size and +2 oxidation state. It is the second most abundant transition metal in living organisms after iron. Zn2+ binding proteins account for nearly 50% of the transcription regulatory proteins in the human genome and require zinc as an essential cofactor in the regulation of gene expression. Numerous enzymes also employ Zn2+ ions in their active sites. Free Zn2+ is released from metalloprotein complexes during oxidative stress with the remainder being bound to proteins or nucleic acids. Other examples of biological roles of Zinc include signal transduction, regulation of apoptosis, neurotransmission, synaptic plasticity and prostate gland function. In humans, Zinc deficiency is associated with many chronic diseases such as renal disease, sickle cell anemia, cirrhosis, some cancers and deficiencies in metabolism. BioVision has developed the EZCell™ Intracellular Zinc Staining Kit (cell-based) which contains a selective and membrane permeable fluorescent probe for detection of intracellular Zinc. We also include a Positive Control that elevates Zinc staining, and cell-permeable Zinc Chelator that reduces fluorescence induced by Positive Control. This easy-to-use non-radioactive assay allows studies of the regulation of Zinc at the cellular level by Fluorescence Microscopy and Flow Cytometry in cultured cells
产品特点
• Simple procedure; takes ~ 2 hours • Fast and convenient • The assay is sensitive, stable, specific and high-throughput adaptable • Applications- the kit can visualize intracellular content in suspension and/or adherent cells
保存建议
-20
其他
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
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