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中文名称

Growth Hormone, Human (hGH) BioAssay ELISA Kit

英文名字
Growth Hormone, Human (hGH) BioAssay ELISA Kit
供应商
USBiological
产品货号
G9000-01
产品报价
¥1/96Tests
产品说明书
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背景资料
USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
产品描述
Human growth hormone (GH) is a 22kD monomeric protein produced and stored in somatotrophs in the anterior pituitary gland. GH is released from the pituitary into the bloodstream in a pulsatile manner under the regulatory control of hypothalamic somatostatin (SS) and GH-releasing factor (GHRF). The timing and frequency of GH release appears to be regulated by somatostatin, while the amplitude of GH release is determined by GHRF. A minor fraction (~10%) of GH in circulation exists in a smaller 20kD form. GH has profound effects on tissue growth and metabolism, which is thought to be mediated through GH-dependent production of IGF-I and IGF-II, and their associated binding proteins. GH apparently stimulates IGF production after binding to specific cell surface receptors in the liver and, possibly, other tissues. Almost 50% of GH in circulation is bound to a high affinity GH binding protein (GHBP), which represents the extracellular domain of the GH receptor. Deficient GH secretion can occur in a number of clinical conditions. However, evaluation of GH deficiency is complicated by the episodic nature of GH secretion and low circulating levels. A variety of physiologic and pharmacologic stimuli have been used to stimulate pituitary GH release during testing and failure to achieve a normal serum GH level in response to at least 2 GH stimulation or provocative tests is considered to be a diagnostic of GH deficiency. The definition of a normal serum GH response is controversial, although published values generally range from 5-10ng/ml. GH excess (or acromegaly) can be caused either by direct GH hypersecretion or GH excess secondary to GHRF hypersecretion.Kit Components:G9000-01A: Microtiter Plate 1x96wellsG9000-01B: Pab (HRP) 1x12mlG9000-01C: Standard (50ng/ml) 1x1 vialG9000-01D: Standard (25ng/ml) 1x1 vialG9000-01E: Standard (12ng/ml) 1x1 vialG9000-01F: Standard (6ng/ml) 1x1 vialG9000-01G: Standard (2ng/ml) 1x1 vialG9000-01H: Standard (0ng/ml) 1x1 vialG9000-01J: Sample Diluent 1x7mlG9000-01K: Substrate A 1x10mlG9000-01L: Substrate B 1x10mlG9000-01M: Stop Solution 1x14mlG9000-01N: Wash Buffer (20 X) 1x60mlSensitivity: ~0.5ng/mlStorage and Stability:Store at 4°C. Stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
产品特点
针对Growth Hormone, Human (hGH) BioAssay ELISA Kit该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Growth Hormone, Human (hGH) BioAssay ELISA Kit产品后将其置于4°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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