Allopregnanolone (3α-hydroxy-5α-pregnan-20-one) is a neurosteroid present in the blood and the brain. Allopregnanolone is made from progesterone which is converted into 5α-dihydroprogesterone by 5α-reductase type I. Allopregnanolone aids neurogenesis and has been found to reverse neuron proliferative deficit and cognitive deficits in a mouse model of Alzheimer’s disease. Allopregnanolone has also been shown to restore functionality in a mouse model of Parkinson’s Disease and to improve behavioral problems in post-traumatic stress disorder. BioVision’s Allopregnanolone ELISA kit is a competitive ELISA assay for the quantitative measurement of Allopregnanolone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue culture media samples.
产品特点
Easy, convenient and time-saving method to measure the level of Allopregnanolone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue.
Detection Range: 10000 – 156.25 pg/ml
Sensitivity: < 129.7 pg/ml
Detection Limit: 65.9 pg/ml
