3.亲水性AqT®接头：TFMP基团是高度疏水的，使用传统的乙烯和乙二醇型接头用TFMP标记的生物分子倾向于聚集并使标记的蛋白质不稳定。T2 A14 AqT®连接体通过将两个苏糖醇连接在一起制成，大大增加了sxLink™的亲水性及其水溶性（2.2 mg/mL饱和溶液）。该分子也具有更好的生物相容性，与其他生物分子的非特异性疏水相互作用降低，允许高载量的苯基二氮杂环丙烯基团。
2. Reversible disulfide for chemical crosslinking of any biomolecule containing a free thiol.
3. Hydrophilic AqT® linkers: TFMP group is highly hydrophobic, biomolecules labeled with a TFMP using a traditional ethylene and ethylene glycol-type linker tend to aggregate and destabilize the labeled protein. T2A14 AqT® linker is made by linking two threitols together, greatly increasing the hydrophilicity of sxLink™ and its water solubility (2.2 mg/mL saturated solution). The molecule is also more biocompatible with decreased non-specific hydrophobic interactions with other biomolecules, allowing high loading of phenyldiazirine groups.
The product is sold as a lyophilized powder in either 1 vial of 250 µg (Cat# CM81401-250UG) or 4 vials of 250 µg (Cat# CM81401-4x250UG). One vial of dissolution buffer is included in each configuration.
