This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.
应用类型
WB,IHC-F,IHC-P,ICC/IF
免疫原
A synthetic phosphopeptide corresponding to residues surrounding Ser47 of human SIRT1
