The NF-κB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IκB proteins. Most agents that activate NF-κB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IκB.
应用类型
WB,IHC-P,ICC/IF,IP,FC
免疫原
A synthesized peptide derived from human IKK gamma