Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.
应用类型
IHC-P,IHC-F,ICC/IF,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human Ubinuclein. AA range:161-210
