Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes.
应用类型
ICC/IF,WB,IHC-F,IHC-P,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220
