The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
应用类型
WB,IHC-P,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180