- 中文名称
TrueBlack®脂褐素自体荧光淬灭剂，20 X DMF溶液
- 英文名字
- TrueBlack
- 供应商
- Biotium
- 产品货号
- BTM-23007
- 产品报价
- ￥询价/1ML
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Features:r
r - Eliminates lipofuscin autofluorescence
r - Reduces autofluorescence from non-lipofuscin sources
r - Doesn't cause high background, unlike Sudan Black B
r - Can be used before or after immunofluorescence staining
r - Clears the way for fluorescence imaging of human and aged animal tissues
r
r TrueBlack® Lipofuscin Autofluorescence Quencher, 20X in DMF, is a new reagent for quenching lipofuscin autofluorescence in tissue sections for immunofluorescence staining. Lipofuscin consists of highly autofluorescent granules of oxidized proteins and lipids that build up in the lysosomes of aging cells. Lipofuscin granules fluoresce brightly in all channels used for fluorescence microscopy, and accumulate in a variety of cell and tissue types with age. Consequently, imaging of specific immunofluorescence signal in certain adult human tissues or aged animal tissues can be virtually impossible unless methods are employed to quench or mask lipofuscin fluorescence.r r Traditionally, Sudan Black B has been used to quench lipofuscin autofluorescence by incubating tissue sections with the dye after immunofluorescence staining. However, while it masks the autofluorescence from lipofuscin, Sudan Black B also introduces uniform non-specific background fluorescence in the red and far-red channels, limiting the use of fluorescent dyes in those wavelengths. Now Biotium has developed TrueBlack® as a superior alternative to Sudan Black B. TrueBlack® quenches lipofuscin fluorescence with far less increase in red/far-red background fluorescence. TrueBlack® treatment can be performed before or after immunostaining. It is rapid, simple, and has minimal effect on signal from fluorescent antibodies or nuclear counterstains, thus preserving the signal-to-noise ratio of the immunostaining.r r TrueBlack® effectively eliminates lipofuscin autofluorescence in tissues like human and mouse brain and retina.
- 产品描述
- TrueBlack®可有效消除人和小鼠大脑和视网膜等组织中的脂褐素自发荧光。 TrueBlack®还可以减少来自其他来源的自发荧光，例如胶原蛋白，弹性蛋白，红细胞和一般背景荧光。它在淬灭这些自发荧光源方面不如它对脂褐素有效，但它可以改善人类和非人类组织类型中的背景。TrueBlack®还用于猝灭聚碳酸酯滤光片上的背景荧光，所述聚碳酸酯滤光片用作成像细胞术的细胞支持物。
- 产品形式
- 该TrueBlack®脂褐素自体荧光淬灭剂，20 X DMF溶液产品形式待更新请参考产品说明书
- 保存建议
- 室温
- 其他
- Biotium公司是一家在荧光技术领域独树一帜的生物技术公司，公司位于美国加利福尼亚的BAY AREA------中外知名首要的生物科技中心。该公司一直致力于开发和生产用于生物医学研究的荧光指示剂及其他特殊生化产品。其产品被广泛应用于细胞生 物学、蛋白质组学、分子生物学、免疫学、微生物学、诊断学、生物化学、神经科学、血液流动检测及大规模药物筛选等众多领域。Biotium公司专利产品众多，包括已经被广泛使用的实时PCR定量荧光染料EvaGreen、具有划时代意义的凝胶核酸染料Gel Red和GelGreen，以及最新推出的Cheetah Taq热启动酶和CF系列蛋白质标记染料等。 n目前，Biotium已将其许多专利技术授权给一些主要的国际生物技术公司，包括安捷伦、BD生物科学、Biolegend、BioRad、EMD Millipore、Illumina、PerkinElmer、Qiagen、Roche、Sartorius AG、Sigma-Aldrich、Thermo Fisher Scientific等。
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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