G-protein coupled receptor for 5-hydroxytryptamine (serotonin. Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
应用类型
WB
免疫原
Recombinant fusion protein of human HTR1F(NP_000857.1).
