- 中文名称
CRLF2 polyclonal antibody
- 英文名字
- CRLF2 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS70875
- 产品报价
- ￥询价/50ul
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- The gene encoding murine TSLP maps to chromosome 18. Its human homologue is expressed in several tissues, including heart, liver and prostate. TSLP mediates its function by binding to a receptor complex: first binding with low affinity to a TSLP-specific chain designated TSLPR, (also designated CRLF2, cytokine receptor-like factor 2), then forming a high affinity complex with the IL-7Ra subunit, which explains the overlapping biological properties between TSLP and IL-7. Both TSLP and IL-7 induce phosphorylation of the transcription factor Stat5, but unlike IL-7, TSLP-mediated signaling does not activate the JAKs. TSLP prevents apoptosis and stimulates the proliferation of myeloid cells, which is supported by the coexpression of TSLPR and IL-7Ra on monocytes and dendritic cells.
- 应用类型
- WB
- 免疫原
- Recombinant protein of human CRLF2.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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