- 中文名称
TGFβ RI (E161) polyclonal antibody
- 英文名字
- TGFβ RI (E161) polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS3257
- 产品报价
- ￥询价/50ul
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- A total of three members of the TGFb family, namely TGFb1, TGFb2 and TGFb3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFbs mediate their activity by high affinity binding to the TGFb receptor type-II (TGFb RII) with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses, TGFb RII requires both its kinase activity and its association with a TGFb-binding protein, designated TGFb receptor type-1 (TGFb RI). TGFb RI is a 503 amino acid single-pass type I membrane protein that is expressed ubiquitously and, with TGFb RII, functions as a receptor for TGFb. Defects in the gene encoding TGFb RI are the cause of aortic aneurysm familial thoracic type 5 (AAT5), Loeys-Dietz syndrome type 2A (LDS2A) and Loeys-Dietz syndrome type 1A (LDS1A).
- 应用类型
- WB
- 免疫原
- Synthetic peptide, corresponding to Human TGFβ RI.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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