BTTAA is a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTAA are advancements from water-insoluble TBTA and are desirable for bio conjugation in diverse chemical biology experiments.nAngew. Chem. Int. Ed., 51: 5852-5856(2012)nNature Communications, 5, 4981 (2014) Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.