Sulfo-Cy3 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy3 is a cyanine dye with excitation and emission maxima at 555 nm and 570 nm respectively. The sulfonate group on the Cy3 dye increases this compound’s water solubility.