NI 57 CAS:1883548-89-7产品的分子式为C19H17N3O4S,分子量为383.42904,
产品描述
NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI 57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI 57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.