Sulfo-Cy3 Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy3 is a cyanine dye with excitation and emission maxima at 555 nm and 570 nm respectively. The sulfonate group on the Cy3 dye increases this compound’s water solubility for easy use in vivo.