- 中文名称
重组IL-17 A,His,人
- 英文名字
- RecombinantIL-17A,His,Human
- 供应商
- Bioworld
- 产品货号
- BK0234
- 产品报价
- ¥询价/10ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- Interleukin-17A (IL-17A),also known as CTLA-8 and IL-17, is a proinflammatory cytokine belonging to the IL-17 family. It is secreted by Th17 cells, gamma/delta T cells, NK cells and neutrophils. IL-17A signals through IL-17 receptor A in a complex with receptor C or D to regulate NF-kappaB and MAP kinase activities. IL-17A plays important roles in the anti-microbial response and chronic inflammation. It stimulates the production of IL-6, IL-8 and G-CSF in epithelial and endothelial cells, and induces the expression of ICAM-1 in fibroblasts. Clinically, IL-17A has been associated with inflammatory diseases, such as rheumatoid arthritis, psoriasis and multiple sclerosis.Recombinant human Interleukin-17A (rhIL-17A) produced in CHO cells is a glycosylated homodimer chain containing 142 amino acids. A fully biologically active molecule, rhIL-17A has a molecular mass of around 14-22 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
- 序列
- GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINAD
GNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVAHHHHHH
- 来源宿主
- CHO
- 溶解建议
- Reconstituted in ddH2O or PBS at 100 μg/ml.
- 保存建议
- Lyophilized recombinant humanInterleukin-17A (IL-17A), His remains stable up to 6 months at -80
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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