- 中文名称
重组OSM,小鼠
- 英文名字
- RecombinantOSM,Mouse
- 供应商
- Bioworld
- 产品货号
- BK0148
- 产品报价
- ¥询价/10ug
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, which also includes IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. In vivo, OSM is secreted from activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF, and shares a receptor with LIF in human. Human OSM can bind to gp130 and recruit OSM Receptor β or LIF Receptor β to form a ternary complex. OSM stimulates the growth of different types of cells, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells. Recombinant Mouse Oncostatin M (rmOSM) produced in E.coli is a single non-glycosylated polypeptide chain containing 182 amino acids. A fully biologically active molecule, rmOSM has a molecular mass of 20.5 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- MNRGCSNSS SQLLSQLQNQ ANLTGNTESL LEPYIRLQNL NTPDLRAACT QHSVAFPSED TLRQLSKPHF LSTVYTTLDR VLYQLDALRQ KFLKTPAFPK
LDSARHNILG IRNNVFCMAR LLNHSLEIPE PTQTDSGASR STTTPDVFNT KIGSCGFLWG YHRFMGSVGR VFREWDDGST RSR
- 来源宿主
- Escherichia coli.
- 溶解建议
- Reconstituted in ddH2O or PBS at 100 μg/ml.
- 保存建议
- Lyophilized recombinant Mouse Oncostatin M (rmOSM) remains stable up to 6 months at -80
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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