中文名称

重组OSM（227aa），人

英文名字

RecombinantOSM(227aa),Human

供应商

Bioworld

产品货号

BK0147

产品报价

￥询价/10ug

产品说明书

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购买方式

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产品新闻

背景资料

Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, including IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. In vivo, OSM is secreted from activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF, and share a receptor with LIF in human. Human OSM can bind to gp130 and recruit OSM Receptor β or LIF Receptor β to form a ternary complex. OSM stimulates the growth of different types of cells, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. On the other hand, OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells.Recombinant human Oncostatin M (rhOSM) produced in E.coli is a single non-glycosylated polypeptide chain containing 228 amino acids. A fully biologically active molecule, rhOSM has a molecular mass of 25.9 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

序列

MAAIGSCSK EYRVLLGQLQ KQTDLMQDTS RLLDPYIRIQ GLDVPKLREH CRERPGAFPS EETLRGLGRR GFLQTLNATL GCVLHRLADL EQRLPKAQDL ERSGLNIEDL EKLQMARPNI LGLRNNIYCM AQLLDNSDTA EPTKAGRGAS QPPTPTPASD AFQRKLEGCR FLHGYHRFMH SVGRVFSKWG ESPNRSRRHS PHQALRKGVR RTRPSRKGKR LMTRGQLPR

来源宿主

Escherichia coli.

溶解建议

Reconstituted in ddH2O at 100 μg/mL.

保存建议

Lyophilized recombinant human Oncostatin M (rhOSM) remains stable up to 6 months at -80

其他

Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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