Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence to a related chemokine, CXCL1. CXCL2 is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. CXCL2 can signal through the CXCR2 receptor.Recombinant mouse MIP-2/CXCL2 produced in E.coli is a single non-glycosylated polypeptide chain containing 73 amino acids. A fully biologically active molecule, rmMIP-2/CXCL2 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
序列
GA VVASELRCQC LKTLPRVDFK NIQSLSVTPP GPHCAQTEVI ATLKGGQKVC LDPEAPLVQK IIQKILNKGK AN
来源宿主
Escherichia coli.
溶解建议
Reconstituted in ddH2O or PBS at 100 μg/ml.
保存建议
Lyophilized recombinant mouse MIP-2/CXCL2 remains stable up to 6 months at -80
