中文名称

重组MIF，人

英文名字

RecombinantMIF,Human

供应商

Bioworld

产品货号

BK0133

产品报价

￥询价/10ug

产品说明书

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购买方式

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产品新闻

背景资料

Macrophage Migration Inhibitory Factor (MIF) is a pleiotropic cytokine, existing as a homotrimer in vivo. MIF was originally identified as a T cell derived factor responsible for the inhibition of macrophage migration. However, recently MIF has received much more attention because of its possible roles in angiogenesis and cancer development. MIF is over-expressed in various cancers, including pancreatic, breast, colon, brain, prostate, skin, and lung. The intratumoral expression of MIF is strongly correlated with angiogenic growth factor expression, such as the expression of Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF), and with risk of recurrence after resection. Recombinant human Macrophage Migration Inhibitory Factor (rhMIF) produced in E.coli is a single non-glycosylated polypeptide chain containing 115 amino acids. rhMIF has a molecular mass of 12.5 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

序列

MPMFIVNTN VPRASVPDGF LSELTQQLAQ ATGKPPQYIA VHVVPDQLMA FGGSSEPCAL CSLHSIGKIG GAQNRSYSKL LCGLLAERLR ISPDRVYINY YDMNAANVGW NNSTFA

来源宿主

Escherichia coli.

溶解建议

Reconstituted in ddH2O at 100 μg/mL.

保存建议

Lyophilized recombinant human Macrophage Migration Inhibitory Factor (rhMIF) remains stable up to 6 months at -80

其他

Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

注意

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