- 中文名称
重组KGF/FGF-7,小鼠
- 英文名字
- RecombinantKGF/FGF-7,Mouse
- 供应商
- Bioworld
- 产品货号
- BK0117
- 产品报价
- ¥询价/10ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF’s roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands., KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney. Recombinant mouse Keratinocyte Growth Factor (rmKGF) produced in E.coli is a single non-glycosylated polypeptide chain containing 163 amino acids. A fully biologically active molecule, rmKGF has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- CND MSPEQTATSV NCSSPERHTR SYDYMEGGDI RVRRLFCRTQ WYLRIDKRGK VKGTQEMKNS YNIMEIRTVA VGIVAIKGVE SEYYLAMNKE GKLYAKKECN EDCNFKELIL ENHYNTYASA KWTHSGGEMF VALNQKGIPV KGKKTKKEQK TAHFLPMAIT
- 来源宿主
- Escherichia coli.
- 溶解建议
- Reconstituted in PBS at 100 μg/ml.
- 保存建议
- Lyophilized recombinant mouse Keratinocyte Growth Factor (rmKGF) remains stable up to 6 months at -80
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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