中文名称

重组KGF/FGF-7，人

英文名字

RecombinantKGF/FGF-7,Human

供应商

Bioworld

产品货号

BK0116

产品报价

￥询价/10ug

产品说明书

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购买方式

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产品新闻

背景资料

Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to the FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of an FGF receptor, FGFR2-IIIb. FGFR2-IIIb is produced by most of the epithelial cells, indicating that KGF plays roles as a paracrine mediator. KGF induces the differen-tiation and proliferation of various epithelial cells, including keratinocytes in the epidermis, hair follicles and sebaceous glands, and is responsible for the wound repairs of various tissues, including lung, bladder, and kidney. Recombinant human Keratinocyte Growth Factor (rhKGF) produced in E.coli is a single non-glycosylated polypeptide chain containing 164 amino acids. A fully biologically active molecule, rhKGF has a molecular mass of 19.0 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

序列

MCN DMTPEQMATN VNCSSPERHT RSYDYMEGGD IRVRRLFCRT QWYLRIDKRG KVKGTQEMKN NYNIMEIRTV AVGIVAIKGV ESEFYLAMNK EGKLYAKKEC NEDCNFKELI LENHYNTYAS AKWTHNGGEM FVALNQKGIP VRGKKTKKEQ KTAHFLPMAI T

来源宿主

Escherichia coli.

溶解建议

Reconstituted in ddH2O at 100 μg/ml.

保存建议

Lyophilized recombinant human Keratinocyte Growth Factor (rhKGF) remains stable up to 6 months at -80

其他

Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

注意

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