中文名称

重组IHH，人

英文名字

RecombinantIHH,Human

供应商

Bioworld

产品货号

BK0088

产品报价

￥询价/10ug

产品说明书

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购买方式

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产品新闻

背景资料

The Indian Hedgehog protein (IHH) is one of three proteins in the mammalian hedgehog family, the others being desert hedgehog (DHH) and Sonic hedgehog (SHH). Hedgehog proteins are important signaling molecules during embryonic development and are highly conserved across species. Mouse and human IHH share 100% amino acid identity in the signaling domain, while mouse IHH and SHH share 90% amino acid identity in the N-terminal signaling domain. IHH mRNA expression is detected in fetal lung, gut, stomach, liver, kidney, pancreas and strongly in cartilage in growth regions of the developing bone. IHH has a specific role in bone growth and differentiation. In addition, IHH is involved in yolk sac vasculogenesis, having a central role in differentiation of epiblast cells into endothelial and red blood cells. IHH gene mutations cause the brachydactyly type A1 which is characterized by shortening or malformation of the phalanges and also the acrocapitofemoral dysplasia.Recombinant Human Indian Hedgehog (IHH) produced in E.coli is a single non-glycosylated polypeptide chain containing 178 amino acids. A fully biologically active molecule, rhIHH has a molecular mass of 20 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

序列

IIG PGRVVGSRRR PPRKLVPLAY KQFSPNVPEK TLGASGRYEG KIARSSERFK ELTPNYNPDI IFKDEENTGA DRLMTQRCKD RLNSLAISVM NQWPGVKLRV TEGWDEDGHH SEESLHYEGR AVDITTSDRD RNKYGLLARL AVEAGFDWVY YESKAHVHCS VKSEHSAAAK TGG

来源宿主

Escherichia coli.

溶解建议

Reconstituted in ddH2O or PBS at 100 μg/ml.

保存建议

Lyophilized recombinant Human Indian Hedgehog (IHH), remains stable up to 6 months at -80

其他

Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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