- 中文名称
重组HB-EGF，人
- 英文名字
- RecombinantHB-EGF,Human
- 供应商
- Bioworld
- 产品货号
- BK0073
- 产品报价
- ￥询价/10ug
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds to the EGF receptor with a higher affinity and has been shown to bemore mitogenic, likely due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has also been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin. Heparin-binding EGF-like growth factor has been shown to interact with NRD1, Zinc finger and BTB domain-containing protein 16 and BAG1.Recombinant Human HB-EGF produced in E.coli cells is a polypeptide chain containing 86 amino acids. A fully biologically active molecule, rhHB-EGF has a molecular mass of 14 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
- 序列
- GD LQEADLDLLR VTLSSKPQAL ATPNKEEHGK RKKKGKGLGK KRDPCLRKYK DFCIHGECKY VKELRAPSCI CHPGYHGERC HGLSL
- 来源宿主
- Escherichia coli.
- 溶解建议
- Reconstituted in ddH2O or PBS at 100 μg/ml.
- 保存建议
- Lyophilized recombinant Human Proheparin-binding EGF-like Growth Factor (HB-EGF), remains stable up to 6 months at -80
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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