- 中文名称
重组FGF酸性,小鼠
- 英文名字
- RecombinantFGF-acidic,Mouse
- 供应商
- Bioworld
- 产品货号
- BK0052
- 产品报价
- ¥询价/10ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- Fibroblast Growth Factor- acidic (FGF-acidic) is a mitogen targeting at the endothelial cells, and belongs to the heparin binding FGF family, which contains 22 members. FGF-acidic binds to the receptor family FGFR1-4 in vivo with the assistance of heparin. However, along with FGF -basic, FGF-acidic lacks the signal peptide segment, and thus is not secreted via endoplasmic reticulum (ER) and Golgi bodies. Studies have shown that FGF-acidic is highly regulated, and it is a direct angiogenesis factor. If unregulated, angiogenesis could contribute to several diseases including arthritis, diabetes, ocular neovascularization, and especially tumors. Therefore, FGF-acidic is treated as a potential oncogene, and its overexpression is correlated tightly with several cancers. Recombinant mouse Fibroblast Growth Factor- acidic (rmFGF-acidic) produced in E.coli is a single non-glycosylated polypeptide chain containing 140 amino acids. A fully biologically active molecule, rmFGF-acidic has a molecular mass of 15.8 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- FNL PLGNYKKPKL LYCSNGGHFL RILPDGTVDG TRDRSDQHIQ LQLSAESAGE VYIKGTETGQ YLAMDTEGLL YGSQTPNEEC LFLERLEENH YNTYTSKKHA EKNWFVGLKK NGSCKRGPRT HYGQKAILFL PLPVSSD
- 来源宿主
- Escherichia coli.
- 溶解建议
- Reconstituted in ddH2O at 100 μg/mL.
- 保存建议
- Lyophilized recombinant mouse Fibroblast Growth Factor- acidic (rmFGF-acidic) remains stable up to 6 months at -80
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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