APP is an integral membrane protein found in any tissues and concentrated in the synapses of neurons. It is known as the precursor molecule generating amyloid beta (Aβ), and the amyloid fibrillar form is the primary component of amyloid plaques found in the brains of patients with Alzheimer's disease.
应用类型
Western blot (WB)
免疫原
Synthetic peptide amino acids: 737-751 of human APP UniProt: P05067 or 85-99 of the C99 generated by secretases.
